Competitive Inhibition Can Linearize Dose-Response and Generate a Linear Rectifier
نویسندگان
چکیده
منابع مشابه
Competitive inhibition can linearize dose-response and generate a linear rectifier.
Many biological responses require a dynamic range that is larger than standard bi-molecular interactions allow, yet the also ability to remain off at low input. Here we mathematically show that an enzyme reaction system involving a combination of competitive inhibition, conservation of the total level of substrate and inhibitor, and positive feedback can behave like a linear rectifier-that is, ...
متن کاملCan arousal modulate response inhibition?
The goal of the present study was to examine if and how arousal can modulate response inhibition. Two competing hypotheses can be drawn from previous literature. One holds that alerting cues that elevate arousal should result in an impulsive response and therefore impair response inhibition. The other suggests that alerting enhances processing of salient events and can therefore enhance process...
متن کاملHow Can Deep Rectifier Networks Achieve Linear Separability and Preserve Distances?
This paper investigates how hidden layers of deep rectifier networks are capable of transforming two or more pattern sets to be linearly separable while preserving the distances with a guaranteed degree, and proves the universal classification power of such distance preserving rectifier networks. Through the nearly isometric nonlinear transformation in the hidden layers, the margin of the linea...
متن کاملSystematic and comprehensive analysis of the dose-response characteristics of a morning quality check of a linear accelerator and an important application of accelerator performance prediction
Background: This paper aimed to analyze the output constancy of a medical linear accelerator using PTW QUICKCHECKwebline and studied the sensitivity of the PTW QUICKCHECKwebline. Materials and Methods: The paper statistically analyzed the output doses of 6 MV and 10 MV of photons and 6 MeV, 9 MeV, and 12 MeV of electrons from a medical linear accelerator measured before the daily treatment to ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Systems
سال: 2015
ISSN: 2405-4712
DOI: 10.1016/j.cels.2015.09.001